| Protein Name | membrane associated ring-CH-type finger 11 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 441061 |
| Gene Symbol | MARCHF11 |
| UniProt | A6NNE9 (MARHB_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
4
Total Number of Articles : 6 |
Description |
membrane associated ring-CH-type finger 11 |
| Gene Summary |
MARCH11 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). These enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their intracellular transport. March11 appears to have a role in ubiquitin-mediated protein sorting in the trans-Golgi network (TGN)-multivesicular body (MVB) transport pathway (Morokuma et al., 2007 [PubMed 17604280]).[supplied by OMIM, Apr 2010] |
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