| Protein Name | ketoreductase |
|---|---|
| Organism | Saccharomyces cerevisiae S288C |
| Gene ID | 852456 |
| Gene Symbol | IFA38 |
| UniProt | P38286 (MKAR_YEAST) |
| Relationships |
Total Number of functionally related compound(s) :
1
Total Number of Articles : 1 |
Description |
ketoreductase |
| Gene Summary |
Enables ketoreductase activity. Involved in fatty acid elongation; sphingolipid biosynthetic process; and very long-chain fatty acid biosynthetic process. Located in endoplasmic reticulum membrane. Used to study cancer; gynecomastia; polycystic kidney disease; and pseudohermaphroditism. Human ortholog(s) of this gene implicated in 17-beta hydroxysteroid dehydrogenase 3 deficiency and disorder of sexual development. Orthologous to several human genes including HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12) and HSDL1 (hydroxysteroid dehydrogenase like 1). [provided by Alliance of Genome Resources, Jul 2025] |
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