Protein Name DNA-directed RNA polymerase core subunit RPC40
Organism Saccharomyces cerevisiae S288C
Gene ID 856226
Gene Symbol

RPC40

UniProt P07703 (RPAC1_YEAST)
Relationships Total Number of functionally related compound(s) : 8
Total Number of Articles : 4
Description

DNA-directed RNA polymerase core subunit RPC40

Gene Summary

Contributes to DNA-directed RNA polymerase activity. Involved in tRNA transcription by RNA polymerase III and transcription by RNA polymerase I. Part of RNA polymerase I complex and RNA polymerase III complex. Used to study Treacher Collins syndrome 2 and hypomyelinating leukodystrophy. Human ortholog(s) of this gene implicated in Treacher Collins syndrome 3 and hypomyelinating leukodystrophy 11. Orthologous to human POLR1C (RNA polymerase I and III subunit C). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • DNA-directed RNA polymerase core subunit RPC40
  • YPR110C
  • RPC5
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Properties