Protein Name ceruloplasmin
Organism Homo sapiens
Gene ID 1356
Gene Symbol


UniProt P00450 (CERU_HUMAN), A5PL27 (A5PL27_HUMAN)
Relationships Total Number of functionally related compound(s) : 910
Total Number of Articles : 1448


Gene Summary

The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Feb 2012]

  • ceruloplasmin
  • ceruloplasmin (ferroxidase)
  • cuproxidase ceruloplasmin
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