CPRiL

OLIG2

oligodendrocyte transcription factor 2

This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. [provided by RefSeq, Jul 2008]

• oligodendrocyte transcription factor 2
• basic domain, helix-loop-helix protein, class B, 1
• class B basic helix-loop-helix protein 1
class E basic helix-loop-helix protein 19
human protein kinase C-binding protein RACK17
oligodendrocyte lineage transcription factor 2
oligodendrocyte-specific bHLH transcription factor 2
protein kinase C-binding protein 2
BHLHB1
OLIGO2
PRKCBP2
RACK17
bHLHe19