Protein Name 5'-nucleotidase, cytosolic II
Organism Mus musculus
Gene ID 76952
Gene Symbol

Nt5c2

UniProt Q3V1L4 (5NTC_MOUSE), E9Q9M1 (E9Q9M1_MOUSE), A0A494B9X3 (A0A494B9X3_MOUSE)
Relationships Total Number of functionally related compound(s) : 293
Total Number of Articles : 236
Description

5'-nucleotidase, cytosolic II

Gene Summary

Enables GMP 5'-nucleotidase activity. Involved in GMP catabolic process to guanine; allantoin metabolic process; and dGMP catabolic process. Located in cytosol. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 45. Orthologous to human NT5C2 (5'-nucleotidase, cytosolic II). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • cytosolic purine 5'-nucleotidase
  • cytosolic 5'-nucleotidase II
  • cytosolic nucleoside phosphotransferase 5'N
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Properties