Protein Name neural precursor cell expressed, developmentally down-regulated 9
Organism Homo sapiens
Gene ID 4739
Gene Symbol

NEDD9

UniProt Q14511 (CASL_HUMAN), A0A087WUD2 (A0A087WUD2_HUMAN), A0A024QZV9 (A0A024QZV9_HUMAN)
Relationships Total Number of functionally related compound(s) : 81
Total Number of Articles : 93
Description

neural precursor cell expressed, developmentally down-regulated 9

Gene Summary

The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

synonyms
  • enhancer of filamentation 1
  • Cas scaffolding protein family member 2
  • Crk-associated substrate related protein Cas-L
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Properties