Protein Name BCL3 transcription coactivator
Organism Homo sapiens
Gene ID 602
Gene Symbol


UniProt P20749 (BCL3_HUMAN), B7Z3N9 (B7Z3N9_HUMAN)
Relationships Total Number of functionally related compound(s) : 278
Total Number of Articles : 165

BCL3 transcription coactivator

Gene Summary

This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq, Jul 2008]

  • B-cell lymphoma 3 protein
  • B cell CLL/lymphoma 3
  • B-cell leukemia/lymphoma 3
Click to show/hide the synonyms