| Protein Name | BCL3 transcription coactivator |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 602 |
| Gene Symbol | BCL3 |
| UniProt | P20749 (BCL3_HUMAN), B7Z3N9 (B7Z3N9_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
278
Total Number of Articles : 165 |
Description |
BCL3 transcription coactivator |
| Gene Summary |
This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq, Jul 2008] |
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