| Protein Name | centromere protein J |
|---|---|
| Organism | Mus musculus |
| Gene ID | 219103 |
| Gene Symbol | Cenpj |
| UniProt | Q569L8 (CENPJ_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
18
Total Number of Articles : 13 |
Description |
centromere protein J |
| Gene Summary |
Predicted to enable several functions, including gamma-tubulin binding activity; identical protein binding activity; and transcription coactivator activity. Acts upstream of or within organelle assembly; positive regulation of non-motile cilium assembly; and smoothened signaling pathway. Located in centriole and ciliary basal body. Is expressed in several structures, including alimentary system; brain; genitourinary system; sensory organ; and vibrissa. Used to study Seckel syndrome. Human ortholog(s) of this gene implicated in Seckel syndrome 4; primary autosomal recessive microcephaly; and primary autosomal recessive microcephaly 6. Orthologous to human CENPJ (centromere protein J). [provided by Alliance of Genome Resources, Apr 2022] |
| synonyms |
|
| Properties | |