Protein Name acyl-CoA dehydrogenase medium chain
Organism Homo sapiens
Gene ID 34
Gene Symbol

ACADM

UniProt P11310 (ACADM_HUMAN), A0A0S2Z366 (A0A0S2Z366_HUMAN), Q5T4U5 (Q5T4U5_HUMAN), B7Z9I1 (B7Z9I1_HUMAN), B4DJE7 (B4DJE7_HUMAN), Q5HYG7 (Q5HYG7_HUMAN), F6YB23 (F6YB23_HUMAN)
Relationships Total Number of functionally related compound(s) : 181
Total Number of Articles : 186
Description

acyl-CoA dehydrogenase medium chain

Gene Summary

This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

synonyms
  • medium-chain specific acyl-CoA dehydrogenase, mitochondrial
  • acyl-CoA dehydrogenase, C-4 to C-12 straight chain
  • acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain
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Properties