| Protein Name | long intergenic non-protein coding RNA, regulator of reprogramming |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 100885779 |
| Gene Symbol | LINC-ROR |
| UniProt | - |
| Relationships |
Total Number of functionally related compound(s) :
160
Total Number of Articles : 137 |
Description |
long intergenic non-protein coding RNA, regulator of reprogramming |
| Gene Summary |
This gene produces a long non-coding RNA that regulates the reprogramming of pluripotent stem cells. This RNA suppresses induction of tumor protein p53 after DNA damage. It is thought to act as a sponge for microRNAs that regulate stem cell factors POU class 5 homeobox 1, Nanog, and SRY-box 2. This RNA may also have a extracellular role in modulating response to hypoxia in hepatocellular cancer cells. Expression of this transcript is associated with tumor progression and epithelial to mesenchymal transition and metastasis. [provided by RefSeq, Dec 2017] |
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