Protein Name Wnt ligand secretion mediator
Organism Danio rerio
Gene ID 406420
Gene Symbol

wls

UniProt F2Z4U3 (F2Z4U3_DANRE), Q7T357 (Q7T357_DANRE)
Relationships Total Number of functionally related compound(s) : 1
Total Number of Articles : 1
Description

Wnt ligand secretion mediator

Gene Summary

Predicted to enable Wnt-protein binding activity. Acts upstream of or within several processes, including brain development; chondrocyte activation; and skeletal system development. Predicted to be located in Golgi membrane. Predicted to be active in endomembrane system and organelle membrane. Is expressed in several structures, including central nervous system; head; inner ear; midbrain neural keel; and neural tube. Human ortholog(s) of this gene implicated in Zaki syndrome. Orthologous to human WLS (Wnt ligand secretion mediator). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • protein wntless homolog
  • G protein-coupled receptor 177
  • wntless Wnt ligand secretion mediator
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Properties