Protein Name mediator complex subunit 1
Organism Mus musculus
Gene ID 19014
Gene Symbol

Med1

UniProt Q925J9 (MED1_MOUSE)
Relationships Total Number of functionally related compound(s) : 43
Total Number of Articles : 35
Description

mediator complex subunit 1

Gene Summary

Enables several functions, including nuclear receptor binding activity; promoter-specific chromatin binding activity; and transcription coregulator activity. Involved in several processes, including camera-type eye development; circulatory system development; and myeloid cell development. Acts upstream of or within several processes, including hemopoiesis; mammary gland development; and regulation of signal transduction. Located in nucleus. Part of mediator complex. Is expressed in several structures, including central nervous system; genitourinary system; gut; hemolymphoid system gland; and lung. Used to study congestive heart failure and dilated cardiomyopathy. Orthologous to human MED1 (mediator complex subunit 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • mediator of RNA polymerase II transcription subunit 1
  • PPAR-binding protein
  • Ppar binding protein
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Properties