| Protein Name | mediator complex subunit 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 19014 |
| Gene Symbol | Med1 |
| UniProt | Q925J9 (MED1_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
43
Total Number of Articles : 35 |
Description |
mediator complex subunit 1 |
| Gene Summary |
Enables several functions, including promoter-specific chromatin binding activity; transcription coactivator activity; and transcription corepressor activity. Involved in several processes, including animal organ development; mRNA transcription by RNA polymerase II; and negative regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including animal organ development; cellular response to hepatocyte growth factor stimulus; and regulation of signal transduction. Located in nucleus. Part of mediator complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and lung. Used to study congestive heart failure and dilated cardiomyopathy. Orthologous to human MED1 (mediator complex subunit 1). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |