Protein Name lactate dehydrogenase B
Organism Rattus norvegicus
Gene ID 24534
Gene Symbol

Ldhb

UniProt P42123 (LDHB_RAT)
Relationships Total Number of functionally related compound(s) : 22
Total Number of Articles : 19
Description

lactate dehydrogenase B

Gene Summary

This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have also been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes X and 9. [provided by RefSeq, Feb 2016]

synonyms
  • L-lactate dehydrogenase B chain
  • LDH heart subunit
  • LDH-B
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Properties