Protein Name REV3 like, DNA directed polymerase zeta catalytic subunit
Organism Homo sapiens
Gene ID 5980
Gene Symbol

REV3L

UniProt O60673 (REV3L_HUMAN), Q9UG47 (Q9UG47_HUMAN)
Relationships Total Number of functionally related compound(s) : 44
Total Number of Articles : 54
Description

REV3 like, DNA directed polymerase zeta catalytic subunit

Gene Summary

The protein encoded by this gene represents the catalytic subunit of DNA polymerase zeta, which functions in translesion DNA synthesis. The encoded protein can be found in mitochondria, where it protects DNA from damage. Defects in this gene are a cause of Mobius syndrome. [provided by RefSeq, Jan 2017]

synonyms
  • DNA polymerase zeta catalytic subunit
  • REV3-like, polymerase (DNA directed), zeta, catalytic subunit
  • Rev-3, yeast, homolog-like (polymerase, DNA, zeta)
Click to show/hide the synonyms
Properties