| Protein Name | nuclear receptor subfamily 0, group B, member 2 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 117274 |
| Gene Symbol | Nr0b2 |
| UniProt | P97947 (NR0B2_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
69
Total Number of Articles : 60 |
Description |
nuclear receptor subfamily 0, group B, member 2 |
| Gene Summary |
Enables nuclear retinoid X receptor binding activity; nuclear thyroid hormone receptor binding activity; and peroxisome proliferator activated receptor binding activity. Involved in several processes, including animal organ regeneration; negative regulation of transcription by RNA polymerase II; and positive regulation of insulin secretion. Part of protein-containing complex. Biomarker of alcoholic hepatitis; diabetes mellitus; and intrahepatic cholestasis. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human NR0B2 (nuclear receptor subfamily 0 group B member 2). [provided by Alliance of Genome Resources, Jun 2025] |
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