Protein Name zinc finger E-box binding homeobox 2b
Organism Danio rerio
Gene ID 564934
Gene Symbol

zeb2b

UniProt B0LVF0 (B0LVF0_DANRE)
Relationships Total Number of functionally related compound(s) : 1
Total Number of Articles : 1
Description

zinc finger E-box binding homeobox 2b

Gene Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including convergent extension; mesenchymal cell differentiation; and regionalization. Predicted to be located in chromosome and nucleoplasm. Is expressed in several structures, including digestive system; nervous system; presumptive mesoderm; tail bud; and vagal neural crest. Human ortholog(s) of this gene implicated in Hirschsprung's disease and Mowat-Wilson syndrome. Orthologous to human ZEB2 (zinc finger E-box binding homeobox 2). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • zinc finger E-box-binding homeobox 2b
  • Smad-interacting protein-1b
  • transcription factor SIP1b
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Properties