| Protein Name | translation initiation factor eIF4A |
|---|---|
| Organism | Saccharomyces cerevisiae S288C |
| Gene ID | 853303 |
| Gene Symbol | TIF2 |
| UniProt | P10081 (IF4A_YEAST) |
| Relationships |
Total Number of functionally related compound(s) :
4
Total Number of Articles : 3 |
Description |
translation initiation factor eIF4A |
| Gene Summary |
Enables RNA helicase activity and translation initiation factor activity. Involved in positive regulation of formation of translation preinitiation complex and translational initiation. Located in cytoplasmic stress granule and plasma membrane. Part of eukaryotic translation initiation factor 4F complex. Human ortholog(s) of this gene implicated in neurodevelopmental disorder with hypotonia and speech delay. Orthologous to human EIF4A1 (eukaryotic translation initiation factor 4A1) and EIF4A2 (eukaryotic translation initiation factor 4A2). [provided by Alliance of Genome Resources, Jun 2025] |
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