Protein Name ssDNA endodeoxyribonuclease RAD1
Organism Saccharomyces cerevisiae S288C
Gene ID 856085
Gene Symbol

RAD1

UniProt P06777 (RAD1_YEAST)
Relationships Total Number of functionally related compound(s) : 47
Total Number of Articles : 47
Description

ssDNA endodeoxyribonuclease RAD1

Gene Summary

Enables single-stranded DNA binding activity. Contributes to single-stranded DNA endodeoxyribonuclease activity. Involved in DNA metabolic process. Located in nucleus. Part of nucleotide-excision repair factor 1 complex. Used to study Fanconi anemia and cancer. Human ortholog(s) of this gene implicated in Fanconi anemia (multiple); XFE progeroid syndrome; pancreatic cancer; polyneuropathy due to drug; and xeroderma pigmentosum (multiple). Orthologous to human ERCC4 (ERCC excision repair 4, endonuclease catalytic subunit). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • ssDNA endodeoxyribonuclease RAD1
  • YPL022W
  • LPB9
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Properties