Protein Name ribonucleotide reductase regulatory subunit M2
Organism Rattus norvegicus
Gene ID 362720
Gene Symbol

Rrm2

UniProt Q4KLN6 (RIR2_RAT)
Relationships Total Number of functionally related compound(s) : 6
Total Number of Articles : 2
Description

ribonucleotide reductase regulatory subunit M2

Gene Summary

Predicted to enable ferric iron binding activity; protein homodimerization activity; and ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor. Involved in positive regulation of cell population proliferation and pyrimidine nucleobase metabolic process. Located in nuclear envelope. Used to study endometrial adenocarcinoma. Biomarker of urinary bladder cancer. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human RRM2 (ribonucleotide reductase regulatory subunit M2). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • ribonucleoside-diphosphate reductase subunit M2
  • Ribonucleotide reductase 2
  • ribonucleotide reductase M2 polypeptide
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Properties