| Protein Name | annexin A2 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 12306 |
| Gene Symbol | Anxa2 |
| UniProt | P07356 (ANXA2_MOUSE), Q542G9 (Q542G9_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
75
Total Number of Articles : 78 |
Description |
annexin A2 |
| Gene Summary |
Predicted to enable several functions, including enzyme binding activity; enzyme inhibitor activity; and phospholipid binding activity. Involved in several processes, including mRNA transcription by RNA polymerase II; positive regulation of low-density lipoprotein particle clearance; and regulation of macromolecule metabolic process. Acts upstream of or within several processes, including collagen fibril organization; fibrinolysis; and response to activity. Located in several cellular components, including Schmidt-Lanterman incisure; basolateral plasma membrane; and myelin sheath adaxonal region. Part of RNA polymerase II transcription regulator complex and plasma membrane protein complex. Is active in cornified envelope. Is expressed in several structures, including central nervous system; dorsal aorta; oral epithelium; primary palate; and yolk sac blood vessel. Human ortholog(s) of this gene implicated in osteonecrosis. Orthologous to several human genes including ANXA2 (annexin A2). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |