| Protein Name | DH domain-containing protein |
|---|---|
| Organism | Caenorhabditis elegans |
| Gene ID | 173748 |
| Gene Symbol | rhgf-2 |
| UniProt | - |
| Relationships |
Total Number of functionally related compound(s) :
2
Total Number of Articles : 1 |
Description |
DH domain-containing protein |
| Gene Summary |
Enables guanyl-nucleotide exchange factor activity and small GTPase binding activity. Involved in several processes, including Rho protein signal transduction; embryonic body morphogenesis; and positive regulation of transcription by RNA polymerase II. Located in axon and cell body. Is expressed in nervous system; pharyngeal cell; seam cell; and tail. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease recessive intermediate C and autosomal recessive distal hereditary motor neuronopathy 4. Orthologous to several human genes including PLEKHG5 (pleckstrin homology and RhoGEF domain containing G5). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |