| Protein Name | Insulin degrading metalloproteinase |
|---|---|
| Organism | Drosophila melanogaster |
| Gene ID | 40248 |
| Gene Symbol | Ide |
| UniProt | P22817 (IDE_DROME) |
| Relationships |
Total Number of functionally related compound(s) :
10
Total Number of Articles : 6 |
Description |
Insulin degrading metalloproteinase |
| Gene Summary |
Enables metallopeptidase activity. Involved in several processes, including insulin catabolic process; negative regulation of insulin receptor signaling pathway; and regulation of trehalose metabolic process. Located in cytoplasm and plasma membrane. Is expressed in several structures, including central nervous system; embryonic/larval digestive system; embryonic/larval fat body; embryonic/larval tracheal system; and imaginal disc. Human ortholog(s) of this gene implicated in Alzheimer's disease and type 2 diabetes mellitus. Orthologous to human IDE (insulin degrading enzyme). [provided by Alliance of Genome Resources, Apr 2022] |
| synonyms |
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| Properties | |