Protein Name gastric inhibitory polypeptide
Organism Homo sapiens
Gene ID 2695
Gene Symbol

GIP

UniProt P09681 (GIP_HUMAN)
Relationships Total Number of functionally related compound(s) : 297
Total Number of Articles : 781
Description

gastric inhibitory polypeptide

Gene Summary

This gene encodes an incretin hormone and belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion. [provided by RefSeq, Jul 2008]

synonyms
  • gastric inhibitory polypeptide
  • glucose-dependent insulinotropic polypeptide
  • incretin hormone
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Properties