| Protein Name | alpha-2-macroglobulin |
|---|---|
| Organism | Mus musculus |
| Gene ID | 232345 |
| Gene Symbol | A2m |
| UniProt | Q6GQT1 (A2MG_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
72
Total Number of Articles : 58 |
Description |
alpha-2-macroglobulin |
| Gene Summary |
Predicted to enable several functions, including cytokine binding activity; growth factor binding activity; and serine-type endopeptidase inhibitor activity. Acts upstream of or within stem cell differentiation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including brain; embryo mesenchyme; liver; meninges; and retina. Human ortholog(s) of this gene implicated in COVID-19; background diabetic retinopathy; multiple sclerosis; neurodegenerative disease (multiple); and obstructive lung disease. Orthologous to human A2M (alpha-2-macroglobulin). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |