| Protein Name | mitogen-activated protein kinase kinase kinase 8 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 26410 |
| Gene Symbol | Map3k8 |
| UniProt | Q07174 (M3K8_MOUSE), Q3UEB8 (Q3UEB8_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
73
Total Number of Articles : 54 |
Description |
mitogen-activated protein kinase kinase kinase 8 |
| Gene Summary |
Predicted to enable MAP kinase kinase kinase activity. Predicted to be involved in MAPK cascade; gap junction-mediated intercellular transport; and positive regulation of inflammatory response. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Is expressed in several structures, including adipose tissue; adrenal gland; alimentary system; hemolymphoid system gland; and reproductive system. Human ortholog(s) of this gene implicated in clear cell renal cell carcinoma; lung cancer; and stomach cancer. Orthologous to human MAP3K8 (mitogen-activated protein kinase kinase kinase 8). [provided by Alliance of Genome Resources, Jun 2025] |
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