| Protein Name | Adaptor Protein complex 1, sigma subunit |
|---|---|
| Organism | Drosophila melanogaster |
| Gene ID | 42835 |
| Gene Symbol | AP-1sigma |
| UniProt | Q9VCF4 (Q9VCF4_DROME), B8A403 (B8A403_DROME), A0A0B4KHB7 (A0A0B4KHB7_DROME) |
| Relationships |
Total Number of functionally related compound(s) :
3
Total Number of Articles : 1 |
Description |
Adaptor Protein complex 1, sigma subunit |
| Gene Summary |
Enables clathrin adaptor activity. Involved in axon guidance and compound eye photoreceptor development. Part of AP-1 adaptor complex. Is expressed in several structures, including adult head; embryonic/larval midgut primordium; and gut section. Human ortholog(s) of this gene implicated in MEDNIK syndrome and syndromic X-linked intellectual disability 5. Orthologous to several human genes including AP1S2 (adaptor related protein complex 1 subunit sigma 2). [provided by Alliance of Genome Resources, Jul 2025] |
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