| Protein Name | interleukin 18 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 29197 |
| Gene Symbol | Il18 |
| UniProt | P97636 (IL18_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
333
Total Number of Articles : 382 |
Description |
interleukin 18 |
| Gene Summary |
Predicted to enable cytokine activity and interleukin-18 receptor binding activity. Involved in several processes, including cellular response to cytokine stimulus; positive regulation of cell population proliferation; and positive regulation of cytokine production. Located in apical plasma membrane and extracellular space. Used to study brain edema; heart disease; status epilepticus; steatotic liver disease; and vasculitis. Biomarker of several diseases, including artery disease (multiple); cardiac arrest; ischemia (multiple); lung disease (multiple); and perinatal necrotizing enterocolitis. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; allergic rhinitis; autoimmune disease (multiple); biliary atresia; and liver disease (multiple). Orthologous to human IL18 (interleukin 18). [provided by Alliance of Genome Resources, Jul 2025] |
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