Protein Name 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
Organism Mus musculus
Gene ID 208715
Gene Symbol

Hmgcs1

UniProt Q8JZK9 (HMCS1_MOUSE)
Relationships Total Number of functionally related compound(s) : 8
Total Number of Articles : 15
Description

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1

Gene Summary

Predicted to enable several functions, including hydroxymethylglutaryl-CoA synthase activity; organic acid binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including acetyl-CoA metabolic process; cellular response to low-density lipoprotein particle stimulus; and farnesyl diphosphate biosynthetic process, mevalonate pathway. Predicted to be located in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human HMGCS1 (3-hydroxy-3-methylglutaryl-CoA synthase 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • hydroxymethylglutaryl-CoA synthase, cytoplasmic
  • 3-hydroxy-3-methylglutaryl coenzyme A synthase
  • HMG-CoA synthase
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Properties