Protein Name 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
Organism Mus musculus
Gene ID 208715
Gene Symbol

Hmgcs1

UniProt Q8JZK9 (HMCS1_MOUSE)
Relationships Total Number of functionally related compound(s) : 8
Total Number of Articles : 15
Description

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1

Gene Summary

Predicted to enable several functions, including hydroxymethylglutaryl-CoA synthase activity; organic acid binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including acetyl-CoA metabolic process; cellular response to low-density lipoprotein particle stimulus; and farnesyl diphosphate biosynthetic process, mevalonate pathway. Predicted to act upstream of or within cholesterol biosynthetic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human HMGCS1 (3-hydroxy-3-methylglutaryl-CoA synthase 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • hydroxymethylglutaryl-CoA synthase, cytoplasmic
  • 3-hydroxy-3-methylglutaryl coenzyme A synthase
  • HMG-CoA synthase
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Properties