Protein Name carbonic anhydrase 7
Organism Homo sapiens
Gene ID 766
Gene Symbol

CA7

UniProt P43166 (CAH7_HUMAN)
Relationships Total Number of functionally related compound(s) : 80
Total Number of Articles : 52
Description

carbonic anhydrase 7

Gene Summary

Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. The cytosolic protein encoded by this gene is predominantly expressed in the brain and contributes to bicarbonate driven GABAergic neuron excitation. Alternative splicing in the coding region results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2018]

synonyms
  • carbonic anhydrase 7
  • carbonate dehydratase VII
  • carbonic anhydrase VII
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Properties