Protein Name protein phosphatase 3, regulatory subunit B, alpha
Organism Rattus norvegicus
Gene ID 29748
Gene Symbol

Ppp3r1

UniProt P63100 (CANB1_RAT)
Relationships Total Number of functionally related compound(s) : 2
Total Number of Articles : 2
Description

protein phosphatase 3, regulatory subunit B, alpha

Gene Summary

Enables phosphoprotein phosphatase activity. Involved in protein dephosphorylation. Predicted to be located in sarcolemma. Predicted to be part of calcineurin complex. Predicted to be active in several cellular components, including Schaffer collateral - CA1 synapse; hippocampal mossy fiber to CA3 synapse; and parallel fiber to Purkinje cell synapse. Biomarker of traumatic brain injury. Human ortholog(s) of this gene implicated in Alzheimer's disease and dilated cardiomyopathy. Orthologous to human PPP3R1 (protein phosphatase 3 regulatory subunit B, alpha). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • calcineurin subunit B type 1
  • protein phosphatase 2B regulatory subunit 1
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Properties