Protein Name serine (or cysteine) preptidase inhibitor, clade A, member 1B
Organism Mus musculus
Gene ID 20701
Gene Symbol

Serpina1b

UniProt P22599 (A1AT2_MOUSE)
Relationships Total Number of functionally related compound(s) : 44
Total Number of Articles : 34
Description

serine (or cysteine) preptidase inhibitor, clade A, member 1B

Gene Summary

Enables serine-type endopeptidase inhibitor activity. Acts upstream of or within several processes, including in utero embryonic development; protein N-linked glycosylation; and response to peptide hormone. Located in extracellular region. Is expressed in gut; liver lobe; nucleus pulposus; and renal calyx. Human ortholog(s) of this gene implicated in several diseases, including alpha 1-antitrypsin deficiency; artery disease (multiple); chronic obstructive pulmonary disease (multiple); inflammatory bowel disease (multiple); and liver disease (multiple). Orthologous to human SERPINA1 (serpin family A member 1). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • alpha-1-antitrypsin 1-2
  • AAT
  • alpha-1 protease inhibitor 2
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Properties