| Protein Name | lysosomal acid lipase A |
|---|---|
| Organism | Mus musculus |
| Gene ID | 16889 |
| Gene Symbol | Lipa |
| UniProt | Q9Z0M5 (LICH_MOUSE), Q3TEL5 (Q3TEL5_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
46
Total Number of Articles : 56 |
Description |
lysosomal acid lipase A |
| Gene Summary |
Predicted to enable sterol esterase activity. Acts upstream of or within several processes, including homeostasis of number of cells within a tissue; lung development; and tissue remodeling. Predicted to be located in cytosol; lysosome; and nuclear lumen. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in several structures, including adrenal cortex zone; alimentary system; brain; hemolymphoid system; and metanephros. Used to study Wolman disease and lysosomal and lipase deficiency. Human ortholog(s) of this gene implicated in Wolman disease; cholesterol ester storage disease; and lysosomal and lipase deficiency. Orthologous to human LIPA (lipase A, lysosomal acid type). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |