Protein Name coagulation factor II (thrombin)
Organism Danio rerio
Gene ID 325881
Gene Symbol

f2

UniProt E7FAN5 (E7FAN5_DANRE), Q7SXH8 (Q7SXH8_DANRE)
Relationships Total Number of functionally related compound(s) : 3
Total Number of Articles : 3
Description

coagulation factor II (thrombin)

Gene Summary

Predicted to enable serine-type endopeptidase activity. Acts upstream of or within blood coagulation. Predicted to be located in extracellular region. Predicted to be active in extracellular matrix and extracellular space. Is expressed in liver and yolk syncytial layer. Human ortholog(s) of this gene implicated in several diseases, including appendicitis; artery disease (multiple); autoimmune disease (multiple); hemophilia (multiple); and thrombophilia (multiple). Orthologous to human F2 (coagulation factor II, thrombin). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • prothrombin
  • wu:fb57c10
  • wu:fd42e09
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Properties