| Protein Name | karyopherin alpha |
|---|---|
| Organism | Saccharomyces cerevisiae S288C |
| Gene ID | 855532 |
| Gene Symbol | SRP1 |
| UniProt | Q02821 (IMA1_YEAST) |
| Relationships |
Total Number of functionally related compound(s) :
16
Total Number of Articles : 20 |
Description |
karyopherin alpha |
| Gene Summary |
Enables nuclear import signal receptor activity. Involved in NLS-bearing protein import into nucleus; proteasome localization; and protein targeting to membrane. Located in cytoplasm and nucleus. Part of NLS-dependent protein nuclear import complex. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 88. Orthologous to several human genes including KPNA5 (karyopherin subunit alpha 5). [provided by Alliance of Genome Resources, Jul 2025] |
| synonyms |
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| Properties | |