| Protein Name | Epidermal growth factor receptor |
|---|---|
| Organism | Drosophila melanogaster |
| Gene ID | 37455 |
| Gene Symbol | Egfr |
| UniProt | P04412 (EGFR_DROME), Q8MLW0 (Q8MLW0_DROME) |
| Relationships |
Total Number of functionally related compound(s) :
68
Total Number of Articles : 80 |
Description |
Epidermal growth factor receptor |
| Gene Summary |
Enables epidermal growth factor-activated receptor activity. Involved in several processes, including animal organ development; oogenesis; and open tracheal system development. Is integral component of plasma membrane. Colocalizes with cytoneme. Is expressed in several structures, including ectoderm anlage; germ layer; gut section; head; and imaginal disc. Used to study alcohol use disorder and cardiomyopathy. Human ortholog(s) of this gene implicated in several diseases, including amyotrophic lateral sclerosis type 19; breast cancer (multiple); carcinoma (multiple); reproductive organ cancer (multiple); and spinal disease (multiple). Orthologous to several human genes including ERBB4 (erb-b2 receptor tyrosine kinase 4). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |