| Protein Name | regulated endocrine-specific protein 18 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 19711 |
| Gene Symbol | Resp18 |
| UniProt | P47939 (RES18_MOUSE), Q8BT93 (Q8BT93_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
5
Total Number of Articles : 2 |
Description |
regulated endocrine-specific protein 18 |
| Gene Summary |
This gene encodes a secreted protein that is expressed mainly in the peripheral endocrine and neuroendocrine tissues and is regulated by physiological factors that include blood glucose and dopaminergic drugs. The encoded protein is found in the lumen of the endoplasmic reticulum and is degraded in the post-ER pre-Golgi compartment. Gene knockout experiments in mice demonstrate that this gene is essential for embryonic development with embryonic lethality occurring before embryonic day 9.5. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016] |
| synonyms |
|
| Properties | |