CPRiL

Protein Name	replication factor C (activator 1) 1
Organism	Mus musculus
Gene ID	19687
Gene Symbol	Rfc1
UniProt	P35601 (RFC1_MOUSE), Q5U4B1 (Q5U4B1_MOUSE), A0A0N5E9G7 (A0A0N5E9G7_MOUSE), G3X8Z6 (G3X8Z6_MOUSE)
Relationships	Total Number of functionally related compound(s) : 20 Total Number of Articles : 22
Description	replication factor C (activator 1) 1
Gene Summary	Predicted to enable several functions, including DNA binding activity; DNA clamp unloader activity; and DNA-binding transcription factor binding activity. Predicted to be involved in DNA-templated DNA replication; negative regulation of transcription by RNA polymerase II; and positive regulation of DNA-templated transcription. Located in nucleus. Is expressed in several structures, including adrenal gland; alimentary system; central nervous system; genitourinary system; and retina. Human ortholog(s) of this gene implicated in West Nile fever and congenital heart disease. Orthologous to human RFC1 (replication factor C subunit 1). [provided by Alliance of Genome Resources, Jun 2025]
synonyms	replication factor C subunit 1 A1 140 kDa subunit A1-P145 ISRE-binding protein RF-C 140 kDa subunit activator 1 140 kDa subunit activator 1 large subunit activator 1 subunit 1 differentiation-specific element-binding protein replication factor C 1 replication factor C 140 kDa subunit replication factor C large subunit replication factor C, 140 kDa 140kDa Alp145 RFC140 Recc1 Click to show/hide the synonyms
Properties