Protein Name replication factor C (activator 1) 1
Organism Mus musculus
Gene ID 19687
Gene Symbol

Rfc1

UniProt P35601 (RFC1_MOUSE), Q5U4B1 (Q5U4B1_MOUSE), A0A0N5E9G7 (A0A0N5E9G7_MOUSE), G3X8Z6 (G3X8Z6_MOUSE)
Relationships Total Number of functionally related compound(s) : 20
Total Number of Articles : 22
Description

replication factor C (activator 1) 1

Gene Summary

Predicted to enable DNA binding activity; DNA clamp unloader activity; and protein domain specific binding activity. Predicted to be involved in DNA clamp unloading; negative regulation of transcription by RNA polymerase II; and positive regulation of transcription, DNA-templated. Located in nucleus. Is expressed in several structures, including adrenal gland; alimentary system; central nervous system; genitourinary system; and retina. Human ortholog(s) of this gene implicated in West Nile fever. Orthologous to human RFC1 (replication factor C subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • replication factor C subunit 1
  • A1 140 kDa subunit
  • A1-P145
Click to show/hide the synonyms
Properties