Protein Name | delta 4-desaturase, sphingolipid 1 |
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Organism | Mus musculus |
Gene ID | 13244 |
Gene Symbol | Degs1 |
UniProt | O09005 (DEGS1_MOUSE) |
Relationships |
Total Number of functionally related compound(s) :
21
Total Number of Articles : 21 |
Description |
delta 4-desaturase, sphingolipid 1 |
Gene Summary |
Enables retinol isomerase activity and sphingolipid delta-4 desaturase activity. Acts upstream of or within ceramide biosynthetic process and positive regulation of apoptotic process. Predicted to be located in mitochondrion. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy. Orthologous to human DEGS1 (delta 4-desaturase, sphingolipid 1). [provided by Alliance of Genome Resources, Apr 2022] |
synonyms |
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Properties | |