Protein Name upstream transcription factor 2
Organism Mus musculus
Gene ID 22282
Gene Symbol

Usf2

UniProt Q64705 (USF2_MOUSE)
Relationships Total Number of functionally related compound(s) : 11
Total Number of Articles : 16
Description

upstream transcription factor 2

Gene Summary

Enables DNA binding activity and DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in glucose mediated signaling pathway; lipid homeostasis; and positive regulation of transcription from RNA polymerase II promoter by glucose. Acts upstream of or within lactation; positive regulation of DNA-templated transcription; and regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including central nervous system; dorsal root ganglion; early conceptus; genitourinary system; and sensory organ. Orthologous to human USF2 (upstream transcription factor 2, c-fos interacting). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • upstream stimulatory factor 2
  • major late transcription factor 2
  • Usf-2
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Properties