Protein Name scaffold attachment factor B
Organism Mus musculus
Gene ID 224903
Gene Symbol

Safb

UniProt D3YXK2 (SAFB1_MOUSE), S4R1M2 (S4R1M2_MOUSE)
Relationships Total Number of functionally related compound(s) : 32
Total Number of Articles : 26
Description

scaffold attachment factor B

Gene Summary

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and chromatin binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within estrogen receptor signaling pathway; hormone metabolic process; and regulation of growth. Predicted to be located in midbody and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; future brain; olfactory epithelium; reproductive system; and retina layer. Orthologous to human SAFB (scaffold attachment factor B). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • scaffold attachment factor B1
  • 3110021E02Rik
  • 5330423C17Rik
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Properties