| Protein Name | peptidylprolyl isomerase F |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 10105 |
| Gene Symbol | PPIF |
| UniProt | P30405 (PPIF_HUMAN), A0A024QZS4 (A0A024QZS4_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
123
Total Number of Articles : 145 |
Description |
peptidylprolyl isomerase F |
| Gene Summary |
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death. [provided by RefSeq, Jul 2008] |
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