Protein Name RNA binding fox-1 homolog 2
Organism Homo sapiens
Gene ID 23543
Gene Symbol

RBFOX2

UniProt O43251 (RFOX2_HUMAN)
Relationships Total Number of functionally related compound(s) : 71
Total Number of Articles : 63
Description

RNA binding fox-1 homolog 2

Gene Summary

This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

synonyms
  • RNA binding protein fox-1 homolog 2
  • RNA binding protein, fox-1 homolog 2
  • RNA-binding motif protein 9
Click to show/hide the synonyms
Properties