Protein Name adhesion G protein-coupled receptor L3
Organism Homo sapiens
Gene ID 23284
Gene Symbol

ADGRL3

UniProt Q9HAR2 (AGRL3_HUMAN), E7EUW2 (E7EUW2_HUMAN), E7ESV6 (E7ESV6_HUMAN), E7EUP0 (E7EUP0_HUMAN), E7EVD6 (E7EVD6_HUMAN), B7Z2G2 (B7Z2G2_HUMAN)
Relationships Total Number of functionally related compound(s) : 66
Total Number of Articles : 36
Description

adhesion G protein-coupled receptor L3

Gene Summary

This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. [provided by RefSeq, Jul 2008]

synonyms
  • adhesion G protein-coupled receptor L3
  • calcium-independent alpha-latrotoxin receptor 3
  • latrophilin homolog 3 (cow)
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Properties