Protein Name TATA box binding protein
Organism Rattus norvegicus
Gene ID 117526
Gene Symbol

Tbp

UniProt Q66HB1 (Q66HB1_RAT)
Relationships Total Number of functionally related compound(s) : 42
Total Number of Articles : 30
Description

TATA box binding protein

Gene Summary

Enables DNA binding activity. Contributes to RNA polymerase II general transcription initiation factor activity. Involved in positive regulation of DNA-templated transcription and spermatogenesis. Part of transcription factor TFIID complex. Human ortholog(s) of this gene implicated in late onset Parkinson's disease; schizophrenia; spinocerebellar ataxia type 17; and type 1 diabetes mellitus. Orthologous to human TBP (TATA-box binding protein). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • TATA-box-binding protein
  • TFIID
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Properties