| Protein Name | phenylethanolamine N-methyltransferase |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 5409 |
| Gene Symbol | PNMT |
| UniProt | P11086 (PNMT_HUMAN), A8MT87 (A8MT87_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
205
Total Number of Articles : 216 |
Description |
phenylethanolamine N-methyltransferase |
| Gene Summary |
The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012] |
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