Protein Name lymphotoxin A
Organism Mus musculus
Gene ID 16992
Gene Symbol

Lta

UniProt P09225 (TNFB_MOUSE), Q542S2 (Q542S2_MOUSE)
Relationships Total Number of functionally related compound(s) : 56
Total Number of Articles : 47
Description

lymphotoxin A

Gene Summary

Predicted to enable cytokine activity. Acts upstream of or within several processes, including lymph node development; positive regulation of immune response; and positive regulation of type II interferon production. Predicted to be located in plasma membrane. Predicted to be active in extracellular space. Is expressed in several structures, including extraembryonic component; gut; hemolymphoid system; liver; and reproductive system. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); glucose metabolism disease (multiple); leishmaniasis (multiple); and lung disease (multiple). Orthologous to human LTA (lymphotoxin alpha). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • lymphotoxin-alpha
  • TNF beta
  • tumor necrosis factor ligand 1e
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Properties