Protein Name tyrosine hydroxylase
Organism Mus musculus
Gene ID 21823
Gene Symbol

Th

UniProt P24529 (TY3H_MOUSE)
Relationships Total Number of functionally related compound(s) : 245
Total Number of Articles : 431
Description

tyrosine hydroxylase

Gene Summary

Predicted to enable several functions, including cation binding activity; oxygen binding activity; and tyrosine 3-monooxygenase activity. Involved in eye development and visual perception. Acts upstream of or within several processes, including dopamine biosynthetic process from tyrosine; dopaminergic synaptic transmission; and learning or memory. Located in several cellular components, including axon; perikaryon; and perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system; cardiovascular system; eye; genitourinary system; and nervous system. Human ortholog(s) of this gene implicated in Parkinson's disease; Parkinsonism; heroin dependence; hypertension; and obesity. Orthologous to human TH (tyrosine hydroxylase). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • tyrosine 3-monooxygenase
  • tyrosine 3-hydroxylase
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Properties