CPRiL

ABL2

ABL proto-oncogene 2, non-receptor tyrosine kinase

This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2009]

• tyrosine-protein kinase ABL2
• Abelson tyrosine-protein kinase 2
• abelson-related gene protein
c-abl oncogene 2, non-receptor tyrosine kinase
tyrosine-protein kinase ARG
v-abl Abelson murine leukemia viral oncogene homolog 2
ABLL
ARG