| Protein Name | BCL2 interacting killer |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 638 |
| Gene Symbol | BIK |
| UniProt | Q13323 (BIK_HUMAN), A0A024R4X6 (A0A024R4X6_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
101
Total Number of Articles : 93 |
Description |
BCL2 interacting killer |
| Gene Summary |
The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins. [provided by RefSeq, Sep 2011] |
| synonyms |
|
| Properties | |